Sherlock Holmes - 221B BAKER STREET. Support this Project on Lego Ideas 🕵️‍♀️🙏

2022.01.24 07:38 Embarrassed_Gold3819 Sherlock Holmes - 221B BAKER STREET. Support this Project on Lego Ideas 🕵️‍♀️🙏

Sherlock Holmes - 221B BAKER STREET. Support this Project on Lego Ideas 🕵️‍♀️🙏 submitted by Embarrassed_Gold3819 to Design [link] [comments]


2022.01.24 07:38 xKeepingMyCoox Why haven't I gotten the achievement on steam

So a few minutes ago I set a lap at Monza 1966( road course ) with a 1:28:435 with the lotus type 49 in hotlapping. For some reason though I haven't gotten the achivement for beating 1:30:000 at this track nor the achivement for beating Clarks 1:28:5
submitted by xKeepingMyCoox to assettocorsa [link] [comments]


2022.01.24 07:38 mlfav101 Rook Irritation Bump or Keloid?

submitted by mlfav101 to PiercingAdvice [link] [comments]


2022.01.24 07:38 Meremadesings Dragon Age 4 Has “No Chance” of Releasing in 2022 – Rumor

Dragon Age 4 Has “No Chance” of Releasing in 2022 – Rumor submitted by Meremadesings to neogaming [link] [comments]


2022.01.24 07:38 chhamallo People telling a very young child to cover up. She's too young for this.

People telling a very young child to cover up. She's too young for this. submitted by chhamallo to Cringetopia [link] [comments]


2022.01.24 07:38 Einulph Making CC

Hello! I'm wondering if anyone has experience with making CCs for TS3 that they would share with me. I have found a mod (EQHD ConfoMod) which makes the model of the horse a bit different from the original and none of the CCs I have downloaded clips to it perfectly anymore (floating manes and saddles, etc) I would like to make some changes to them so they won't look so wobbly. Obviously I don't want to take any credit for making them and don't want to upload them anywhere (except if the original artist of the mod agrees with it) but I want my game to look pretty with that model. Any help is appreciated!
submitted by Einulph to sims3cc [link] [comments]


2022.01.24 07:38 AsgardUwU My game crashes when I'm in the last Catalina's mission in Gta San Andreas The definitive Edition

My game crashes when I'm in the last Catalina's mission, but it happens only in this mission, I haven't experienced any crashes during the gameplay until now. What should I do? BTW: The game crashes in the middle of the mission.
submitted by AsgardUwU to GTA [link] [comments]


2022.01.24 07:38 noxinanis555 Best approach to create a map editor for my game engine

So, I made an engine which I use for some of my games. The problem is, that currently I have to write the map script files in a text editor. But I want to provide a map editor to visually place the world objects in a map.
I never did such a tool yet, so this is something new. I am thinking of two ways how I could accomplish that:
1) I just create a DirectX application and create the interface completely on my own.
2) I use a GUI system and therefore could use .NET (in my case it would be managed C++, because I don't really like C#)
The first one would definitely be makeable, but it would be connected with a huge amount of work. The second possibility is kinda a new area, because I don't really know how the best approach would be to create a GUI that also contains the view of the map.
Are there any more options? Maybe there are already opensource map editors that I could easily adapt?
How would you approach this?
BTW: The engine is a 2D singleplayer topdown shooter engine written in C++.
submitted by noxinanis555 to gamedev [link] [comments]


2022.01.24 07:38 teamzeros Is there a way to view the "... has achieved mastery ... with ...." message after exiting end game chat?

I always make sure to screenshot my mastery levels (it's just a weird habit) but recently I forgot to screenshot my m4 message for Zeri so I was wondering if there is a way to view those again?
submitted by teamzeros to leagueoflegends [link] [comments]


2022.01.24 07:38 Ricosss Sodium-Glucose Cotransporter 2 Inhibitors Mechanisms of Action: A Review (Pub Date: 2021-12-20)

https://doi.org/10.3389/fmed.2021.777861
Sodium-Glucose Cotransporter 2 Inhibitors Mechanisms of Action: A Review Abstract Sodium-Glucose Cotransporter 2 inhibitors (SGLT2i), or gliflozins, are a group of antidiabetic drugs that have shown improvement in renal and cardiovascular outcomes in patients with kidney disease, with and without diabetes. In this review, we will describe the different proposed mechanisms of action of SGLT2i. Gliflozins inhibit renal glucose reabsorption by blocking the SGLT2 cotransporters in the proximal tubules and causing glucosuria. This reduces glycemia and lowers HbA1c by ~1.0%. The accompanying sodium excretion reverts the tubuloglomerular feedback and reduces intraglomerular pressure, which is central to the nephroprotective effects of SGLT2i. The caloric loss reduces weight, increases insulin sensitivity, lipid metabolism, and likely reduces lipotoxicity. Metabolism shifts toward gluconeogenesis and ketogenesis, thought to be protective for the heart and kidneys. Additionally, there is evidence of a reduction in tubular cell glucotoxicity through reduced mitochondrial dysfunction and inflammation. SGLT2i likely reduce kidney hypoxia by reducing tubular energy and oxygen demand. SGLT2i improve blood pressure through a negative sodium and water balance and possibly by inhibiting the sympathetic nervous system. These changes contribute to the improvement of cardiovascular function and are thought to be central in the cardiovascular benefits of SGLT2i. Gliflozins also reduce hepcidin levels, improving erythropoiesis and anemia. Finally, other possible mechanisms include a reduction in inflammatory markers, fibrosis, podocyte injury, and other related mechanisms. SGLT2i have shown significant and highly consistent benefits in renal and cardiovascular protection. The complexity and interconnectedness of the primary and secondary mechanisms of action make them a most interesting and exciting pharmacologic group.
------------------------------------------ Info ------------------------------------------
Open Access: True (not always correct)
Authors: * Jorge I. Fonseca-Correa * Ricardo Correa-Rotter
Additional links: * https://www.frontiersin.org/articles/10.3389/fmed.2021.777861/pdf * https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720766
submitted by Ricosss to ketoscience [link] [comments]


2022.01.24 07:38 MAFiA_79 Earn 10,000 #Terk by doing easy tasks. #BSCGem #BSCtoken #BSC #Airdrop

Earn 10,000 #Terk by doing easy tasks. #BSCGem #BSCtoken #BSC #Airdrop submitted by MAFiA_79 to CryptoMoon [link] [comments]


2022.01.24 07:38 NewsElfForEnterprise KBR Awarded Early Works Contract for Sustainability-Focused Project by Biojet AS

KBR Awarded Early Works Contract for Sustainability-Focused Project by Biojet AS submitted by NewsElfForEnterprise to News_Chemical [link] [comments]


2022.01.24 07:38 twentyfivebuckduck Need unscented deodorant for partner

Hey! Let me know if this is the wrong place to put this
I’m pregnant and super sensitive to smells. My husband usually wears Oldspice gel deodorant (not antiperspirant) but we switched him to the native unscented stuff instead because when he entered a room I just barfed.
Well he hates it. It doesn’t work against BO as well, it feels yucky in his armpits, but the fact that it’s unscented makes me FINALLY able to stand being near him, so he insists on still using the new stuff.
Does anybody know of any unscented deodorants, (especially if they’re gel) that work well? I can just tell he’s uncomfortable all day and it bothers me because it feels like an additional unnecessary pregnancy hardship.
submitted by twentyfivebuckduck to Mommit [link] [comments]


2022.01.24 07:38 GoldenMidasAJ Take your time to understand it

Take your time to understand it submitted by GoldenMidasAJ to dankmemes [link] [comments]


2022.01.24 07:38 Cheeki99 On the lookout while we were rowing the boat

On the lookout while we were rowing the boat submitted by Cheeki99 to aww [link] [comments]


2022.01.24 07:38 MagicOfTheForest Circulating supply

Does anyone know what is circulating supply of mco2? Cant find it anywhere
submitted by MagicOfTheForest to mco2 [link] [comments]


2022.01.24 07:38 Tomas_Valach Game ignores my mouse ini settings in MO2 (CGO ABR TDM setup)

Hey. I'm almost finished modding and I was just setting up ELFX related stuff and suddenly (didn't install nor removes any mod) my in-game mouse settings is extremely sensitive in X direction (camera to the left and right) and extremely low sensitivity in Y direction (up and down).
I'm using MO2 therefore SKSE takes settings from MO2 skyrim.ini. But no matter how I set these lines it ignores it. I can only affect the sensitivity in general (not much) but it completely ignores the Y/X ratio fMouseHeadingSensitivityMax= fMouseHeadingXScale= fMouseHeadingYScale=
I tried out: Moving in-game sensitivity bar Reseted ini files using Bethini and vanilla Vsync on and off Searched through MCM menu for potential causes like TDMs camera lock Searched every corner of the internet
The only way to hotfix it was to set my Y direction to 16k DPI in my mouse manufacturer software which is pretty inconvenient way to hotfix the issue.
Any ideas what should I try? Thank you for your time
My modlist: "0003","Unofficial Skyrim Special Edition Patch" "0004","Alternate Start - Live Another Life - SSE" "0005","Project New Reign - Nemesis Unlimited Behavior Engine" "0006","True Directional Movement - Modernized Third Person Gameplay" "0007","Combat Gameplay Overhaul SE" "0008","Address Library for SKSE Plugins" "0009","MCM Helper" "0010","SkyUI" "0011","SkyUI SE - Flashing Savegames Fix" "0012","JContainers SE for SKSE 2.19" "0013",".NET Script Framework" "0014","Bug Fixes SSE" "0015","Project New Reign - Nemesis PCEA" "0016","SmoothCam" "0017","SmoothCam - Modern Camera Preset" "0018","Dynamic Animation Replacer" "0019","Attack Behavior Revamp" "0020","Unblockable" "0021","Animation Motion Revolution Ice-skating Fix" "0022","Odin - Skyrim Magic Overhaul" "0023","ODIN spells for NPCS" "0024","Apocalypse - Magic of Skyrim" "0025","Summermyst - Enchantments of Skyrim" "0026","Andromeda - Unique Standing Stones of Skyrim" "0027","powerofthree's Tweaks" "0028","Spell Perk Item Distributor (SPID)" "0029","Seriously Improved Sparks" "0030","Deflection - Dynamic Combat Overhaul" "0031","VioLens - A Killmove Mod SE" "0032","Better SmoothCam Preset" "0033","OnHit Animations Framework - SSE" "0034","Flinching Needs This" "0035","FlinchingSSE" "0036","zxlice hitStop SSE - Script Free" "0037","Disable screen shake effect" "0038","Wildcat - Combat of Skyrim" "0039","Truly Undead - Reborn SE" "0040","Skyrim Revamped - Complete Enemy Overhaul" "0041","Arena - An Encounter Zone Overhaul" "0042","Sovngarde - A Nordic Font" "0043","Noble Skyrim Mod HD-2K" "0044","Static Mesh Improvement Mod" "0045","High Poly Project" "0046","Ruins Clutter Improved SE" "0047","JS Dragon Claws - Patches" "0048","Embers HD" "0049","Ultimate HD Fire Effects SSE" "0050","KD - Realistic Fireplaces SE" "0051","Blended Roads" "0053","Enhanced Lights and FX" "0054","ELFX Fixes" "0055","ELFX - Exteriors Fixes" "0056","Dynamic Volumetric Lighting and Sun Shadows" "0057","Dolomite Weathers - Natural Lighting Vivid Atmospherics II" "0058","Dynamic Volumetric Lighting and Sun Shadows Patch" "0059","Quick Light SE" "0060","Dungeon Darkness SE" "0061","Lanterns Of Skyrim II" "0062","Skyrim Flora Overhaul SE" "0063","Realistic Water Two SE" "0064","Flora Respawn Fix" "0065","Better Harvesting" "0066","Relationship Dialogue Overhaul - RDO SE Prej ma byt po alt start" "0067","Faster Mining Plus SE" "0068","Remember Lockpick Angle - Updated" "0069","A Quality World Map" "0070","Enhanced Blood Textures" "0071","Immersive Citizens - AI Overhaul" "0072","Total Character Makeover" "0073","Immersive Patrols SE" "0074","Immersive Sounds - Compendium" "0075","The Paarthurnax Dilemma" "0076","Ars Metallica - Smithing Enhancement" "0077","OBIS SE - Organized Bandits In Skyrim Special Edition" "0078","Lucien - Immersive Fully Voiced Male Follower" "0079","Footprints" "0080","Run For Your Lives" "0081","Wet and Cold SE" "0082","Diverse Dragons Collection SE (DDCse)" "0083","Cloaks of Skyrim SSE" "0084","Unread Books Glow SSE" "0085","INIGO" "0086","Bandolier - Bags and Pouches Classic" "0087","Sofia - The Funny Fully Voiced Follower" "0088","Guards Armor Replacer SSE" "0089","JS Dragon Claws SE" "0090","Left Hand Rings Modified SE" "0091","JS Purses and Septims SE" "0092","Caliente's Beautiful Bodies Enhancer -CBBE-" "0093","Faster Firewood Harvesting" "0094","Radzig - Johnskyrim" "0095","8K Night Skies - Stars and Galaxies - Cathedral Concept" "0096","Auto Hide Ammo" "0097","Improved Traps" "0098","HD Reworked Horses" "0099","RUSTIC CLOTHING - Special Edition" "0100","Cathedral - Armory" "0101","IMAGINATOR - Visual Control Device for Skyrim" "0102","IMAGINATOR - Visual Control Device for Skyrim Opt" "0104","xEdit Output" "0105","Nemesis Output" "0106","Reduced Glow FX SE"
submitted by Tomas_Valach to skyrimmods [link] [comments]


2022.01.24 07:38 Qcumber2807 Am I the only one who thinks that the "subscribe to a comment" feature is really helpful for this subreddit?

submitted by Qcumber2807 to AskOuija [link] [comments]


2022.01.24 07:38 hamdaan-78 Flashbacks to vik in the recent moresidemen vid

Flashbacks to vik in the recent moresidemen vid submitted by hamdaan-78 to ksi [link] [comments]


2022.01.24 07:38 thenightoaster Always seeking the Unseen [Fujica AX-3, 50mm F2.0, Ilford HP4]

submitted by thenightoaster to analog [link] [comments]


2022.01.24 07:38 sheepy313 BitMart Exchange Listing in 2 Days

What are your thoughts on this listing. I myself is very Excited about the News. Just downloaded the Exchange App and it is very easy to do KYC. Trading is quite straightforward too.
submitted by sheepy313 to MadVikingGames [link] [comments]


2022.01.24 07:38 bingbong_wingwong CoinMarketCap Twitter poll. You know what to do.

CoinMarketCap Twitter poll. You know what to do. submitted by bingbong_wingwong to SafeMoon [link] [comments]


2022.01.24 07:38 Key-Zookeepergame398 TV-Sender Arte: Doku über verstorbenen Hardy Krüger

submitted by Key-Zookeepergame398 to Deutschland_News [link] [comments]


2022.01.24 07:38 Aron_Que_Marr The Corner (2000) from David Simon (creator of The Wire)

submitted by Aron_Que_Marr to fulltvshowsonyoutube [link] [comments]


2022.01.24 07:38 nerbo-martius Seeking the French telephone number to reach the support team, thanks

submitted by nerbo-martius to R6Extraction [link] [comments]


http://katrisestone.ru